Research and Clinical Trials

Completed $200 million private placement post period Phase 3 COPD clinical trials planned to start later this year Pilot clinical study in patients hospitalized with COVID-19 planned to start in the third quarter Conference Call Today at 9:00 am EDT / 2:00 pm BST LONDON and RALEIGH, N.C., Aug. 14, 2020 (GLOBE NEWSWIRE) — Verona
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Pfizer and BioNTech Covid-19 vaccine candidate yields promising results. Credit: BioNTech SE. Sign up here for GlobalData’s free bi-weekly Covid-19 report on the latest information your industry needs to know. Pfizer and BioNTech have reported positive, preliminary results from the ongoing Phase I/II clinical trial of mRNA-based Covid-19 vaccine candidate, BNT162b1, in the US. Peer-reviewed
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Lundbeck announced a decision to discontinue a phase II proof of concept clinical study of Lu AF11167 in patients with schizophrenia who are experiencing persistent negative symptoms. The decision to stop the trial is based on the results of a futility interim analysis, which concluded that the trial is unlikely to achieve statistical significance on its primary endpoint,
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The global Covid-19 pandemic has impacted clinical research significantly. Focusing primarily on oncology, clinical research disruptions involving experimental cancer therapeutics raise severe challenges, as these trials can be highly time-sensitive and even small administrative delays can prove highly detrimental to patient populations. As shown in Figure 1, solid tumour studies currently lead as the indication
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Reviewed by Emily Henderson, B.Sc.Aug 13 2020 Key knowledge gaps exist in our understanding of how ocean microplastics transport bacteria and viruses – and whether this affects the health of humans and animals, researchers say. With millions of tons of plastic reaching the world’s oceans every year – and trillions of particles floating on the
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Holston Medical Group announced Monday that its facilities in Bristol, Tennessee and Kingsport were selected for Project Lightspeed, the global clinical research program centering on the mRNA-based BNT162 COVID-19 vaccine developed by BioNTech SE and Pfizer Inc. The worldwide trial seeking 30,000 has arrived in this part of Appalachia, in Northeastern Tennessee. The local Tri-Cities
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Reviewed by Emily Henderson, B.Sc.Aug 13 2020 A software-based on artificial intelligence (AI), which was developed by researchers at the Eye Clinic of the University Hospital Bonn, Stanford University and University of Utah, enables the precise assessment of the progression of geographic atrophy (GA), a disease of the light sensitive retina caused by age-related macular
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Aerovate Therapeutics has closed on $72.6 million in Series A funding to advance trials of AV-101, an inhaled, dry powder aerosol version of imatinib to treat pulmonary arterial hypertension (PAH). The Series A for Aerovate, which was founded and incubated by RA Capital Management, is led by Sofinnova Investments, a new investor in the company. Atlas
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Print this page PLYMOUTH MEETING, Pa., Aug. 10, 2020 /PRNewswire/ — INOVIO (NASDAQ:INO), a biotechnology company focused on rapidly bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases and cancer, today reported financial results for the quarter ended June 30, 2020.  Dr. J. Joseph Kim, INOVIO’s President and Chief
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Reify developed ‘StudyTeam’ to upgrade the systems health care staff at clinical research sites depend on to run trials. Credit: Darko Stojanovic from Pixabay. Sign up here for GlobalData’s free bi-weekly Covid-19 report on the latest information your industry needs to know. Cloud-based solutions provider Reify Health has raised $30m through Series B financing to
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A new study is the first to show a food-based approach using clinically-proven diet interventions to lower cholesterol levels, such as Step One Foods®, provides significant healthcare cost savings. The study, publishing online in the journal Current Cardiology Reports, analyzed the healthcare costs associated with having elevated low-density lipoprotein cholesterol (LDL-C) levels among commercially insured
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THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION FOR THE PURPOSES OF ARTICLE 7 OF EU REGULATION 596/2014. Acacia Pharma Group plc Interim Results for the Six Months ended 30 June 2020 US approval for BARHEMSYS® for postoperative nausea & vomiting (PONV) US approval of BYFAVO™ for procedural sedation Strategic agreement with Cosmo Technologies providing funding for US
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Print this page CAMBRIDGE, Mass.–(BUSINESS WIRE)–Aug. 11, 2020– Moderna, Inc., (Nasdaq: MRNA) a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients, today announced that the U.S. government has secured 100 million doses of mRNA-1273 as part of the U.S. government’s goal of securing early access to safe and effective
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GeneCentric Therapeutics has announced a research collaboration with Janssen Research & Development on RNA-based drug response biomarkers for non-muscle invasive bladder cancer (NMIBC). Both companies have not disclosed the financial terms of the deal. The research will include the application of GeneCentric’s advanced RNA-based molecular profiling platform to illustrate the potential signatures of disease progression
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Boehringer Ingelheim announced that the first patient has enrolled in InPedILD, a global Phase III trial assessing the dosing and safety profile of nintedanib in children and adolescents between six and 17 years old with clinically significant fibrosing interstitial lung disease (ILD). Childhood ILD (chILD) includes more than 200 rare respiratory disorders that can affect
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Blade Therapeutics announced that the Phase 2 clinical study of the company’s investigational therapeutic, BLD-2660, has enrolled half of the anticipated 120 coronavirus disease-19 (COVID-19) pneumonia patients. Started in May 2020, BLADE-CONQUER (ClinicalTrials.gov NCT04334460) is a double-blind, placebo-controlled clinical trial assessing the efficacy and safety of BLD-2660 on lung function and recovery time in hospitalized
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Boehringer will assess the dose-exposure and safety of nintedanib in paediatric patients. Credit: Madras150. Sign up here for GlobalData’s free bi-weekly Covid-19 report on the latest information your industry needs to know. Boehringer Ingelheim has started patient enrolment for the Phase III InPedILD clinical trial of nintedanib in children and adolescents aged six to 17
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Interview conducted by Emily Henderson, B.Sc.Aug 13 2020 Thought LeadersProfessor Graham PockleyDirectorJohn van Geest Cancer Research Centre Professor Pockley among other researchers from the John van Geest Cancer Research Centre have recently developed a blood test for the detection of prostate cancer. News-Medical spoke to Professor Pockley to find out more! What provoked your research
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Reports out of Israel now suggest that an Israel medical center has a branch in Moscow that is working on going on Gamaleya vaccine research. Although Vladimir Putin recently declared that the Gamaleya vaccine is complete, done, and authorized by health authorities, Phase 3 clinical trials, in addition to so-called “Expanded Use” studies, continue to
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California-based Vir Biotechnology plans to launch a phase 2/3 trial this month of VIR-7831, its investigational neutralizing monoclonal antibody for the treatment of COVID-19 patients. The antibody was shown to neutralize the SARS-CoV-2 virus in preclinical studies. Vir said it also plans to evaluate the drug for the prevention of COVID-19 infections.   The company
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Print this page NEW YORK and MAINZ, GERMANY, August 12, 2020 — Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced that preliminary, peer-reviewed data from their BNT162 mRNA-based vaccine development program, Project Lightspeed, against SARS-CoV-2, were published online in the journal Nature. These preliminary clinical data on BNT162b1, a nucleoside-modified messenger RNA (modRNA) candidate that encodes an optimized
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13 August The UK economy is entering recession, having recorded its biggest contraction in history in Q2 due to the Covid-19 pandemic. The lockdown measures implemented due to the Covid-19 pandemic caused the UK GDP to contract by 20.4% in the second quarter of 2020. Stephany Griffith-Jones, an economist specialising on financial crises, tweeted on
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Sponsored Content by PittconAug 13 2020 Thought LeadersAmanda Hummon, PhDAssociate ProfessorOhio State University An interview with Amanda Hummon PhD, Associate Professor from Ohio State University, discussing how mass spectrometry can be used to analyze the proteome and how this can help with the study of human disease. How is mass spectrometry used to study the
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Willis-Knighton Health System in Shreveport, Louisiana seeks patients who have been diagnosed with laboratory-confirmed SARS-CoV-2 (COVID-19) to help investigate a drug to treat COVID-19. The Louisiana-based health system was selected by Regeneron to participate in this government supported study investigating advanced monoclonal antibodies known as REGN-COV2, targeting COVID-19. TrialSite reviews this research site which recently released
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